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Evidence method

We grade every supplement and device on a simple A/B/C scale:

  • A — Consistent human RCT evidence. Multiple randomized controlled trials show the same effect.
  • B — Promising human evidence. Smaller or mixed studies, but a plausible mechanism and net-positive picture.
  • C — Early, mechanistic or observational evidence. Interesting, but not definitively proven.
  • We update grades as new research is published. Editorial lead: Ulrik Ditlev Eriksen, author of The Art of Longevity.